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fentanyl transdermal and pentobarbital both equally boost sedation. Steer clear of or Use Alternate Drug. Restrict use to people for whom choice treatment method alternatives are inadequate

pentobarbital will lower the extent or outcome of tamoxifen by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.

pentobarbital will reduce the extent or influence of tinidazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.

Watch Carefully (one)pentobarbital will boost the degree or result of clopidogrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism.

pentobarbital will reduce the level or impact of norgestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Moderate CYP3A4 inducers might lower progestin concentration; contemplate use of extra barrier techniques

pentobarbital will minimize the level or result of cyclosporine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

pentobarbital will lower the level or effect of cannabidiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Keep an eye on Closely. Contemplate an increase in cannabidiol dosage (according to scientific response and tolerability) when coadministered with a strong CYP3A4 inducer.

pentobarbital will lower the extent or effect of carbamazepine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.

pentobarbital will lower the extent or influence of voriconazole by affecting hepatic enzyme CYP2C9/ten metabolism. Slight/Importance Mysterious.

pentobarbital will lower the level or effect of imatinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Unknown.

pentobarbital will decrease the level or outcome of itraconazole by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Unfamiliar.

pentobarbital will reduce the extent or effect of saxagliptin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unknown.

pentobarbital will reduce the level or outcome of efavirenz by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unidentified.

Phenytoin and barbiturate blood degrees really should be monitored additional routinely if check here supplied concurrently; impact of barbiturates on phenytoin metabolism noted to be variable; sodium valproate and valproic acid appear to decrease barbiturate metabolism; observe barbiturate blood levels and make appropriate dosage adjustments as necessary